Dental Admissions Test (DAT) Practice Test

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Which part of the egg do sperm cells bind to during human fertilization?

  1. Cytoplasm

  2. Eggshell

  3. Nucleus

  4. Zona Pellucida

The correct answer is: Zona Pellucida

During human fertilization, sperm cells bind to the zona pellucida, which is a glycoprotein layer surrounding the plasma membrane of the egg cell. This binding is crucial for a successful fusion between the sperm cell and the egg cell, leading to the formation of a zygote. The zona pellucida plays a key role in allowing only one sperm cell to penetrate and fertilize the egg, preventing polyspermy. Therefore, option D is the correct answer.

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